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HABSelect Clinical trial

Hyaluronic Acid Binding Sperm selection
‘Increasing live births and reducing miscarriages’

HABSelect is a large, randomised study assessing the effectiveness of a new method of sperm selection for ICSI by prior hyaluronic acid binding, in couples undergoing ICSI treatment.  It has two components; a clinical trial and a parallel laboratory based investigations.

Recruitment will take place in Fertility Clinics throughout the UK and will start at the end of 2013.  We aim to recruit 3730 couples.

The total study recruitment period is expected to last for 21 months and then follow up will continue till the last pregnancy outcome is known. We plan to complete the study recruitment in the second half of 2015.

The study is a collaboration between the University of Leeds (UK) and its partners, supported by the Pragmatic Clinical Trials Unit, Queen Mary University London (UK) and is funded by a UK National Institute of Health Research Efficacy and Mechanisms Evaluation (NIHR-EME) grant.